What is SLE?
Systemic Lupus Erythematosus (SLE) is a chronic, auto-immune disease of unknown cause where the patient’s body makes large quantities of blood proteins called anti-bodies that react against the person’s own tissues.
History
Lupus is the Latin word for wolf. Erythematosus means red rashes. In 1851, Dr. Cazenave discovered red rashes on a patient’s face that looked like wolf bites. He named the rash Discoid Lupus Erythematosus (DLE).
In 1885, Sir William Osler recognised that many people with lupus had a disease involving not only the skin but many other organs or systems. He named the disease Systemic Lupus Erythematosus (SLE).
Types of Lupus
Discoid Lupus Erythematosus (DLE)
• Only involves the skin
• Rarely spreads to other organs
Systematic Lupus Erythematosus (SLE)
• Can spread to other organs
• Can be fatal
Statistics
About 90% of SLE sufferers are women while about 10% are men and children.
About 90% of women with SLE are in their childbearing years, within the range of 15 to 50 years old.
Ratio of SLE sufferers :
In the West, among Afro-Carribeans 1 in 250-500 people
USA – 1 in 2,000 people
China – 1 in 1,000 people
In Malaysia, it is estimated that more than 10,000 people have been diagnosed with SLE over the past 30 years. However, this number may be only the tip of the iceberg. The Malaysian SLE Association believes that there are many more SLE sufferers in Malaysia who have not been diagnosed.
Pagalavan's Avatar 
dear doc,
im a medical student.i want to know why women who have lupus are at higher risk of miscarrying??
thank you for your time.
It is a immune related disease and as such, like any other immune diseases, the risk of miscarriage is higher. SLE patients are also prone to have anti- phospholipid antibodies which is associated with blood clots and miscarriage.
doc,
does SLE harm to people or we harm to them?
and what kind of medication should be given for them?
SLE is a disease that harms an individual. Your own immune system attacks your own body! Treatment consist of steroids and drugs that suppress immune system.